CD47 Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with C-mFc tag. The predicted molecular weight is 48-65 KDa and the accession number is Q08722.
规格 | 价格/CNY | 货期 | 数量 | |
---|---|---|---|---|
10 μg | ¥ 540 | 5日内发货 | ||
50 μg | ¥ 1,410 | 5日内发货 | ||
500 μg | ¥ 9,960 | 5日内发货 | ||
1 mg | ¥ 17,400 | 5日内发货 |
生物活性 | Loaded Anti-Human CD47 mAb-Fc on AHC Biosensor, can bind Human CD47-mFc with an affinity constant of 0.08 nM as determined in BLI assay. (Regularly tested) |
产品描述 | CD47 Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with C-mFc tag. The predicted molecular weight is 48-65 KDa and the accession number is Q08722. |
种属 | Human |
表达系统 | HEK293 Cells |
标签 | C-mFc |
蛋白编号 | Q08722 |
别名 | CD47, IAP, Integrin-associated protein, Antigenic surface determinant protein OA3, MER6, Leukocyte surface antigen CD47, Protein MER6 |
氨基酸序列 | Gln19-Pro139 |
蛋白构建 | Gln19-Pro139 |
分子量 | 48-65 KDa (reducing condition) |
内毒素 | < 0.1 ng/µg (1 EU/µg) as determined by LAL test. |
缓冲液 | Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. |
复溶方法 | Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing. |
存储 |
Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted proteinsolutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
运输方式 |
In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice. |
研究背景 | CD47(Integrin-Associated Protein,IAP) is a 40 ‑ 60 kDa variably glycosylated atypical member of the immunoglobulin superfamily. The ubiquitously expressed CD47 binds to SIRP family members on macrophages, neutrophils, and T cells. CD47 is involved in the increase in intracellular calcium concentration that occurs upon cell adhesion to extracellular matrix. The protein is also a receptor for the C-terminal cell-binding domain of thrombospondin, and it may play a role in membrane transport and signal transduction. This protein has broad tissue distribution, and is reduced in expression on Rh erythrocytes. |
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CD47 Protein, Human, Recombinant (mFc) MER-6 CD47 CD-47 IAP MER 6 Integrin-associated protein Antigenic surface determinant protein OA3 MER6 Leukocyte surface antigen CD47 Protein MER6 CD 47 recombinant recombinant-proteins proteins protein