CD30/TNFRSF8 Protein, Human, Recombinant (aa 19-379, hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 90-120 KDa and the accession number is P28908.
规格 | 价格/CNY | 货期 | 数量 | |
---|---|---|---|---|
10 μg | ¥ 500 | 5日内发货 | ||
50 μg | ¥ 1,170 | 5日内发货 | ||
500 μg | ¥ 8,860 | 5日内发货 | ||
1 mg | ¥ 12,600 | 5日内发货 |
产品描述 | CD30/TNFRSF8 Protein, Human, Recombinant (aa 19-379, hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 90-120 KDa and the accession number is P28908. |
种属 | Human |
表达系统 | Human Cells |
标签 | C-Fc |
蛋白编号 | P28908 |
别名 | TNFRSF8, Ki-1 antigen, CD30, CD30L receptor, Tumor necrosis factor receptor superfamily member 8, Lymphocyte activation antigen CD30 |
氨基酸序列 | Phe19-Lys379 |
蛋白构建 | Recombinant Human Tumor Necrosis Factor Receptor Superfamily Member 8 is produced by our Mammalian expression system and the target gene encoding Phe19-Lys379 is expressed with a human IgG1 Fc tag at the C-terminus. |
蛋白纯度 | Greater than 95% as determined by reducing SDS-PAGE. (QC verified) |
分子量 | 90-120 KDa, reducing conditions |
内毒素 | Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test. |
缓冲液 | Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. |
复溶方法 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
存储 |
Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
运输方式 |
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature listed below. |
研究背景 | CD30, also known as TNFRSF8, is a cell membrane protein of the tumor necrosis factor receptor family, which regulates proliferation/apoptosis and antibody responses. CD30 is expressed by activated, but not by resting, T and B cells. Aberrant expression of CD30 by mastocytosis mast cells and interaction with its ligand CD30L (CD153) appears to play an important role in the pathogenesis and clinical presentation of systemic mastocytosis. CD30 has been considered as a specific diagnostic biomarker of anaplastic large cell lymphoma (ALCL) and classical Hodgkin lymphoma (cHL). CD30 is also a biomarker used for targeted therapy by an antibody–drug conjugate. |
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CD30/TNFRSF8 Protein, Human, Recombinant (aa 19-379, hFc) CD 30 CD-30 TNFRSF8 Ki-1 antigen CD30 TNFRSF 8 CD30L receptor Tumor necrosis factor receptor superfamily member 8 TNFRSF-8 Lymphocyte activation antigen CD30 recombinant recombinant-proteins proteins protein