CD27, also known as TNFRSF7, is an approximately 55 kDa transmembrane protein in the TNF receptor superfamily. It functions as a co‑stimulatory molecule that supports lymphocyte activation and survival. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis.
规格 | 价格/CNY | 货期 | 数量 | |
---|---|---|---|---|
100 μg | ¥ 2,660 | 5日内发货 | ||
500 μg | ¥ 10,600 | 5日内发货 | ||
1 mg | ¥ 17,800 | 5日内发货 |
生物活性 | Immobilized Cynomolgus CD27, His Tag at 1μg/ml (100μl/well) on the plate. Dose response curve for Human CD27 Ligand, hFc Tag with the EC50 of 0.23μg/ml determined by ELISA. |
产品描述 | CD27, also known as TNFRSF7, is an approximately 55 kDa transmembrane protein in the TNF receptor superfamily. It functions as a co‑stimulatory molecule that supports lymphocyte activation and survival. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. |
种属 | Cynomolgus |
表达系统 | HEK293 Cells |
标签 | C-His |
蛋白编号 | G7N5M1 |
别名 | CD27 antigen, S152. LPFS2, S152, TNFRSF7, Tp55, T14 |
蛋白构建 | Thr21-Ile192 |
蛋白纯度 | > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC |
分子量 | 20.41 kDa (predicted). Due to glycosylation, the protein migrates to 42-52 kDa based on Tris-Bis PAGE result. |
内毒素 | < 1 EU/μg by the LAL method. |
缓冲液 | Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS (pH 7.4). Typically, 8% trehalose is incorporated as a protective agent before lyophilization. |
复溶方法 | Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing. |
存储 |
It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted proteinsolutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
运输方式 |
In general, Lyophilized powders are shipping with blue ice. |
研究背景 | CD27, also known as TNFRSF7, is an approximately 55 kDa transmembrane protein in the TNF receptor superfamily. It functions as a co‑stimulatory molecule that supports lymphocyte activation and survival. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. |
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CD27/TNFRSF7 Protein, Cynomolgus, Recombinant (His) S-152 CD27 antigen S 152 S152. LPFS2 S152 TNFRSF 7 T 14 T-14 TNFRSF7 Tp55 T14 TNFRSF-7 recombinant recombinant-proteins proteins protein