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BCMA/TNFRSF17 Protein, Cynomolgus, Recombinant (His)

BCMA/TNFRSF17 Protein, Cynomolgus, Recombinant (His)

产品编号 TMPJ-01446
别名: B-cell maturation protein, CD269, Bcma, Tnfrsf17, Bcm, Tumor necrosis factor receptor superfamily member 17

BCMA/TNFRSF17 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 12 and 15-20 KDa and the accession number is G7Q0I4.

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BCMA/TNFRSF17 Protein, Cynomolgus, Recombinant (His)
规格 价格/CNY 货期 数量
10 μg ¥ 550 5日内发货
50 μg ¥ 1,670 5日内发货
500 μg ¥ 14,800 5日内发货
1 mg ¥ 22,200 5日内发货
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产品目录号及名称: BCMA/TNFRSF17 Protein, Cynomolgus, Recombinant (His) (TMPJ-01446)
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产品性质
产品描述 BCMA/TNFRSF17 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 12 and 15-20 KDa and the accession number is G7Q0I4.
种属 Cynomolgus
表达系统 HEK293 Cells
标签 C-6xHis
蛋白编号 G7Q0I4
别名 B-cell maturation protein, CD269, Bcma, Tnfrsf17, Bcm, Tumor necrosis factor receptor superfamily member 17
氨基酸序列 Met1-Ala53
蛋白构建 Met1-Ala53
蛋白纯度 Greater than 90% as determined by reducing SDS-PAGE. (QC verified)
分子量 12&15-20 KDa (reducing condition)
内毒素 < 0.1 ng/µg (1 EU/µg) as determined by LAL test.
缓冲液 Lyophilized from a solution filtered through a 0.22 μm filter, containing 50 mM Tris-HCl, 100 mM Glycine, pH 7.5.
复溶方法 Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
存储

Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted protein solutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

运输方式

In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.

研究背景 B cell maturation antigen (BCMA) is a member of the TNF receptor superfamily. It has been designated TNFRSF17. BCMA is a type III membrane protein containing one extracellular cysteine rich domain. Within the TNFRSF, it shares the highest homology with TACI. BCMA and TACI have both been shown to bind to APRIL and BAFF, members of the TNF ligand superfamily. BCMA expression has been found in immune organs and mature B cell lines. Although some expression has been observed at the cell surface, BCMA appears to be localized to the Golgi compartment. The binding of BCMA to APRIL or BAFF has been shown to stimulate IgM production in peripheral blood B cells and increase the survival of cultured B cells. This data suggests that BCMA may play an important role in B cell development,function and regulation.

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Keywords

BCMA/TNFRSF17 Protein, Cynomolgus, Recombinant (His) B-cell maturation protein CD 269 CD269 Bcma Tnfrsf17 Bcm CD-269 Tumor necrosis factor receptor superfamily member 17 recombinant recombinant-proteins proteins protein

 

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