BCMA/TNFRSF17 Protein, Cynomolgus, Recombinant (hFc)

BCMA/TNFRSF17 Protein, Cynomolgus, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 38-45 KDa and the accession number is G7Q0I4.

规格	价格/CNY		数量
10 μg	￥ 820	5日内发货
50 μg	￥ 2,480	5日内发货
500 μg	￥ 12,100	5日内发货
1 mg	￥ 17,400	5日内发货

规格

价格/CNY

货期

数量

10 μg

￥ 820

5日内发货

50 μg

￥ 2,480

5日内发货

500 μg

￥ 12,100

5日内发货

1 mg

￥ 17,400

5日内发货

生物活性	1. Loaded Human APRIL-His on HIS1K Biosensor, can bind Cynomolgus BCMA-Fc with an affinity constant of 0.54 nM as determined in BLI assay. (Regularly tested) 2. Immobilized Human APRIL -Flag-His at 1μg/ml (100 μl/well) can bind Cynomolgus BCMA-Fc. The ED50 of Cynomolgus BCMA-Fc is 4.23 ng/ml. (Regularly tested)
产品描述	BCMA/TNFRSF17 Protein, Cynomolgus, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 38-45 KDa and the accession number is G7Q0I4.

种属	Cynomolgus
表达系统	HEK293 Cells
标签	C-hFc
蛋白编号	G7Q0I4
别名	Bcma, Tnfrsf17, B-cell maturation protein, Bcm, CD269, Tumor necrosis factor receptor superfamily member 17
氨基酸序列	Met1-Ala53
蛋白构建	Met1-Ala53
蛋白纯度	Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
分子量	38-45 KDa, reducing conditions

内毒素	< 0.1 ng/µg (1 EU/µg) as determined by LAL test.
缓冲液	Lyophilized from a solution filtered through a 0.22 μm filter, containing 50 mM Tris-HCl, 100 mM Glycine, pH 7.5.
复溶方法	Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
存储	Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted proteinsolutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
运输方式	In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.
研究背景	B cell maturation antigen (BCMA) is a member of the TNF receptor superfamily. It has been designated TNFRSF17. BCMA is a type III membrane protein containing one extracellular cysteine rich domain. Within the TNFRSF, it shares the highest homology with TACI. BCMA and TACI have both been shown to bind to APRIL and BAFF, members of the TNF ligand superfamily. BCMA expression has been found in immune organs and mature B cell lines. Although some expression has been observed at the cell surface, BCMA appears to be localized to the Golgi compartment. The binding of BCMA to APRIL or BAFF has been shown to stimulate IgM production in peripheral blood B cells and increase the survival of cultured B cells. This data suggests that BCMA may play an important role in B cell development,function and regulation.

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BCMA/TNFRSF17 Protein, Cynomolgus, Recombinant (hFc)

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