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B7-2 Protein, Rabbit, Recombinant (His)

B7-2 Protein, Rabbit, Recombinant (His)

产品编号 TMPJ-00959
别名: CD86, T-lymphocyte activation antigen CD86, Activation B7-2 antigen

B7-2 Protein, Rabbit, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 38-70 KDa and the accession number is P42071.

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B7-2 Protein, Rabbit, Recombinant (His)
规格 价格/CNY 货期 数量
10 μg ¥ 580 5日内发货
50 μg ¥ 1,170 5日内发货
500 μg ¥ 5,930 5日内发货
1 mg ¥ 8,300 5日内发货
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产品目录号及名称: B7-2 Protein, Rabbit, Recombinant (His) (TMPJ-00959)
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产品描述 B7-2 Protein, Rabbit, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 38-70 KDa and the accession number is P42071.
种属 Rabbit
表达系统 HEK293 Cells
标签 C-6xHis
蛋白编号 P42071
别名 CD86, T-lymphocyte activation antigen CD86, Activation B7-2 antigen
氨基酸序列 Ala23-Arg246
蛋白构建 Ala23-Arg246
蛋白纯度 Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
分子量 38-70 KDa (reducing condition)
内毒素 < 0.1 ng/µg (1 EU/µg) as determined by LAL test.
缓冲液 Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4.
复溶方法 Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
存储

Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted proteinsolutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

运输方式

In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.

研究背景 T-lymphocyte activation antigen CD86 (B7-2) is a glycosylated protein in the B7 family. B7 family members are transmembrane cell surface molecules that play important roles in immune activation and the maintenance of immune tolerance. It is highly expressed on activated antigen presenting cells. CD86 involved in the costimulatory signal essential for T-lymphocyte proliferation and interleukin-2 production, by binding CD28 or CTLA-4. It may play a critical role in the early events of T-cell activation and costimulation of naive T-cells, such as deciding between immunity and anergy that is made by T-cells within 24 hours after activation. It is expressed by activated B-lymphocytes and monocytes and promoted by MARCH8 and results in endocytosis and lysosomal degradation.

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Keywords

B7-2 Protein, Rabbit, Recombinant (His) CD86 T-lymphocyte activation antigen CD86 Activation B7-2 antigen CD-86 CD 86 recombinant recombinant-proteins proteins protein

 

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