B2M/beta 2-Microglobulin Protein, Cynomolgus, Recombinant (hFc)

B2M/beta 2-Microglobulin Protein, Cynomolgus, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 40 KDa and the accession number is Q8SPW0.

规格	价格/CNY		数量
10 μg	￥ 350	5日内发货
50 μg	￥ 1,070	5日内发货
500 μg	￥ 8,600	5日内发货
1 mg	￥ 12,800	5日内发货

规格

价格/CNY

货期

数量

10 μg

￥ 350

5日内发货

50 μg

￥ 1,070

5日内发货

500 μg

￥ 8,600

5日内发货

1 mg

￥ 12,800

5日内发货

产品描述	B2M/beta 2-Microglobulin Protein, Cynomolgus, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 40 KDa and the accession number is Q8SPW0.

种属	Cynomolgus
表达系统	HEK293 Cells
标签	C-hFc
蛋白编号	Q8SPW0
别名	B2M, Beta-2-Microglobulin, β-2-Microglobulin
氨基酸序列	Ile21-Met119
蛋白构建	Ile21-Met119
蛋白纯度	Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
分子量	40 KDa (reducing condition)

内毒素	< 0.1 ng/µg (1 EU/µg) as determined by LAL test.
缓冲液	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4.
复溶方法	Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
存储	Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted proteinsolutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
运输方式	In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.
研究背景	β-2-Microglobulin (B2M) is a secreted protein with 1 Ig-like C1-type (immunoglobulin-like) domain which belongs to the beta-2-microglobulin family. B2M component of major histocompatibility complex (MHC) class I molecules, involved in the presentation of peptide antigens to the immune system. Polymers of beta 2-microglobulin can be found in tissues from patients on long-term hemodialysis. B2M is a protein found on the surface of many cells and plentiful on the surface of white blood cells. Serum B2M concentration is increased in renal diseases, various malignant diseases and some inflammatory and autoimmune disorders. B2M may adopt the fibrillar configuration of amyloid in certain pathologic states. The capacity to assemble into amyloid fibrils is concentration dependent. B2M has been shown as a marker for monitoring inflammatory disease activity and it appears likely to have a destructive role in amyloidosis-related arthritis. B2M might be involved in the OA (osteoarthritis) pathogenesis. Defects in B2M are the cause of hypercatabolic hypoproteinemia. Affected individuals show marked reduction in serum concentrations of immunoglobulin and albumin, probably due to rapid degradation. B2M could be a potential therapeutic target in ovarian cancer.

计算器

复溶计算器

重组蛋白稀释计算器

比活力计算器

Volume (to add to vial)

Mass (in vial)

Desired Reconstitution Concentration

bottom

B2M/beta 2-Microglobulin Protein, Cynomolgus, Recombinant (hFc)

计算器

技术支持

Keywords