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4-1BB Ligand/TNFSF9 Protein, Human, Recombinant (His & Flag)

4-1BB Ligand/TNFSF9 Protein, Human, Recombinant (His & Flag)

产品编号 TMPJ-00138
别名: Tumor necrosis factor ligand superfamily member 9, 4-1BBL, TNFSF9, 4-1BB ligand

4-1BB Ligand/TNFSF9 Protein, Human, Recombinant (His & Flag) is expressed in HEK293 mammalian cells with N-6xHis-Flag tag. The predicted molecular weight is 30 KDa and the accession number is P41273.

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4-1BB Ligand/TNFSF9 Protein, Human, Recombinant (His & Flag)
规格 价格/CNY 货期 数量
10 μg ¥ 550 5日内发货
50 μg ¥ 1,670 5日内发货
500 μg ¥ 13,700 5日内发货
1 mg ¥ 20,500 5日内发货
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产品目录号及名称: 4-1BB Ligand/TNFSF9 Protein, Human, Recombinant (His & Flag) (TMPJ-00138)
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生物活性
技术参数
产品性质
生物活性 Loaded Human 4-1BB-Fc-His on Protein A Biosensor, can bind Human 4-1BBL-His-Flag with an affinity constant of 4.53 pM as determined in BLI assay. (Regularly tested)
产品描述 4-1BB Ligand/TNFSF9 Protein, Human, Recombinant (His & Flag) is expressed in HEK293 mammalian cells with N-6xHis-Flag tag. The predicted molecular weight is 30 KDa and the accession number is P41273.
种属 Human
表达系统 Human Cells
标签 N-6His-Flag
蛋白编号 P41273
别名 Tumor necrosis factor ligand superfamily member 9, 4-1BBL, TNFSF9, 4-1BB ligand
氨基酸序列 Arg71-Glu254
蛋白构建 Recombinant Human 4-1BB Ligand is produced by our Mammalian expression system and the target gene encoding Arg71-Glu254 is expressed with a 6His, Flag tag at the N-terminus.
蛋白纯度 Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
分子量 30 KDa, reducing conditions
内毒素 Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test.
缓冲液 Lyophilized from a 0.2 μm filtered solution of 20mM Tris-HCl, 500mM NaCl, 5% Trehalose,5% Mannitol, 0.01% Tween80, 1mM EDTA, pH8.0.
复溶方法 Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. 
存储

Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.

运输方式

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature listed below.

研究背景 Tumor necrosis factor ligand superfamily member 9(4-1BBL) is single-pass type II membrane protein which is a member of the the tumor necrosis factor family. 4-1BBL is a 254 amino acids cytokine that is expressed in brain, placenta, lung, skeletal muscle and kidney. TNFSF9 has been shown to reactivate anergic T lymphocytes in addition to promoting T lymphocyte proliferation. This cytokine may have a role in activation-induced cell death (AICD) and cognate interactions between T-cells and B-cells/macrophages. It has also been shown to be required for the optimal CD8 responses in CD8 T cells, and is thought to be involved in T cell-tumor cell interaction.

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Keywords

4-1BB Ligand/TNFSF9 Protein, Human, Recombinant (His & Flag) TNFSF 9 TNFSF-9 Tumor necrosis factor ligand superfamily member 9 4-1BBL TNFSF9 4-1BB ligand recombinant recombinant-proteins proteins protein

 

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