4-1BB/CD137/TNFRSF9 Protein, Cynomolgus, Recombinant (hFc)

4-1BB/CD137/TNFRSF9 Protein, Cynomolgus, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 60 KDa and the accession number is A9YYE7.

规格	价格/CNY		数量
10 μg	￥ 580	5日内发货
50 μg	￥ 1,370	5日内发货
500 μg	￥ 6,640	5日内发货
1 mg	￥ 9,490	5日内发货

规格

价格/CNY

货期

数量

10 μg

￥ 580

5日内发货

50 μg

￥ 1,370

5日内发货

500 μg

￥ 6,640

5日内发货

1 mg

￥ 9,490

5日内发货

生物活性	Loaded Human 4-1BBL-His on HIS1K Biosensor, can bind Cynomolgus 4-1BB-Fc with an affinity constant of <10^-3 nM as determined in BLI assay. (Regularly tested)
产品描述	4-1BB/CD137/TNFRSF9 Protein, Cynomolgus, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 60 KDa and the accession number is A9YYE7.

种属	Cynomolgus
表达系统	Human Cells
标签	C-Fc
蛋白编号	A9YYE7
别名	4-1BB ligand receptor, CD137, CDw137, ILA, TNFRSF9, T-cell antigen 4-1BB homolog, T-cell antigen ILA
氨基酸序列	Leu24-Gln186
蛋白构建	Recombinant Cynomolgus 4-1BB ligand Receptor is produced by our Mammalian expression system and the target gene encoding Leu24-Gln186 is expressed with a human IgG1 Fc tag at the N-terminus.
蛋白纯度	Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
分子量	60 KDa, reducing conditions

内毒素	Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test.
缓冲液	Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
复溶方法	Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
存储	Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.
运输方式	The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature listed below.
研究背景	Tumor necrosis factor receptor superfamily member 9(TNFRSF9), also known as CD137 and 4-1BB, is an inducible T cell surface protein belonging to the tumor necrosis factor receptor superfamily. It is a single-pass type I membrane protein which contains 4 TNFR-Cys repeats. The human and mouse proteins share 60% amino acid sequence identity. CD137 is expressed by mesenchymal cells, including endothelial cells, chondrocytes, and cells of the central nervous system. CD137 is also broadly expressed by cells of the human immune system, is broadly expressed by cells of the human immune system, including activated CD8+ and CD4+ T cells, activated natural killer (NK) cells, follicular dendritic cells (FDCs) and monocytes. CD137 has diverse roles in the immune response, the one key function is to promote the survival of both T cells and dendritic cells by binding the cognate ligand CD137L (4-1BBL).

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4-1BB/CD137/TNFRSF9 Protein, Cynomolgus, Recombinant (hFc)

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